Encyclopedic Reference of Molecular Pharmacology by Stefan Offermanns, Walter Rosenthal

By Stefan Offermanns, Walter Rosenthal

This complete encyclopedic reference offers swift entry to centred info on molecular pharmacology for learn scientists, clinicians and complex scholars. With the A-Z structure of round 2000 entries, approximately 2 hundred authors offer an entire connection with the realm of molecular pharmacology. The booklet combines the information of vintage pharmacology describing drug motion in addition to the newer process of the right research of the molecular mechanisms through which medications exert their results. brief key-phrase entries outline universal acronyms, phrases and words. moreover, certain essays offer in-depth info on medicines, mobile methods, molecular objectives, thoughts, molecular mechanisms and normal rules.

Show description

Read Online or Download Encyclopedic Reference of Molecular Pharmacology PDF

Best pharmacy books

Structural genomics on membrane proteins

Whereas the genomic revolution has speedy resulted in the deposit of  greater than 30,000 buildings within the protein info financial institution (PDB), lower than one percentage of these contributions signify membrane proteins even though membrane proteins represent a few 20 percentage of all proteins. This discrepancy turns into considerably challenging while it's coupled with the truth that 60 percentage of present medicinal drugs are according to focusing on this workforce of proteins, a pattern that doesn't appear more likely to opposite.

Ergot Alkaloids and Related Compounds

With contribution by means of a number of specialists

Biotechnology and biopharmaceuticals : transforming proteins and genes into drugs

Biotechnology and Biopharmaceuticals: reworking Proteins and Genes into medicinal drugs, moment version addresses the pivotal concerns in relation to translational technology, together with preclinical and scientific drug improvement, regulatory technological know-how, pharmaco-economics and cost-effectiveness concerns. the hot variation additionally presents an replace on new proteins and genetic drugs, the translational and built-in sciences that proceed to gasoline the recommendations in drugs, in addition to the recent parts of healing improvement together with melanoma vaccines, stem phone therapeutics, and cell-based remedies.

Drug Metabolism Prediction

The 1st specialist reference in this hugely suitable subject, for drug builders, pharmacologists and toxicologists. The authors offer greater than a scientific evaluate of computational instruments and information bases for drug metabolism examine and their underlying rules. they target to express their specialist wisdom distilled from decades of expertise within the box.

Extra info for Encyclopedic Reference of Molecular Pharmacology

Example text

Whereas types I-III are dependent on antibodies, the type IV reaction is mediated by cellular immune reactions. Type I reaction, anaphylactic reaction This type of allergic reaction is by far the most common one, and may be responsible for more than 80% of all allergies. Often it is used synonymously with allergy. In some individuals, exposure to an antigen then termed allergen - leads to the increased production of specific IgE, a subclass of antibodies A 20 Allergy Fig. 1 Type I Anaphylactic Reaction: IgE-bearing mast cells are activated by allergens to release mediators of acute allergic reactions.

G. musculoskeletal, ᭤ neuropathic, inflammatory) pain. Acute and cancer-related pain are commonly treatable with opioids, NSAIDs and/or local anesthetic blocks. g. psychological, physiotherapeutic) treatment strategies. g. oral, intravenous, subcutaneous, intrathecal, ᭤ epidural, topical, intraarticular, transnasal) are used depending on the clinical circumstances (4). g. g. associated with surgery, child birth) and some selected chronic pain syndromes. g. morphine, codeine, methadone, fentanyl and its derivatives) are µ-agonists.

IgE binds with high affinity to receptors (Fcε-receptors) that are present on basophilic granulocytes and most prominently on the closely related mast cells. These cells thus acquire a “borrowed” (as it is, of course, synthesized by B-lymphocytes) allergen specific receptor, which can persist on these cells for long periods, at least several months, perhaps years. e. sensitized to an allergen without exhibiting any clinical symptoms and without knowing it. Upon re-exposure to this specific allergen, the mast cells (and the other IgE bearing cells) can immediately recognize the allergen with its IgE antibodies.

Download PDF sample

Rated 4.36 of 5 – based on 30 votes