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Enzyme Immunoassays: From Concept to Product Development by S.S. Deshpande

By S.S. Deshpande

`... all those that learn this ebook might be a long way richer of their wisdom of enzyme immunoassays and their application.'
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And SCHICK, A. 1961. On the formation of covalent linkages between two protein molecules. J. Bio!. Chern. 236:2477-248l. , and HEMMILA, 1. 1979. F1uoroimmunoassay: present status and key problems. Clin. Chern. 25:353-36l. STEWARD, M. W. 1984. Antibodies. Their Structure and Function. Chapman & Hall, New York. , and KABAT, E. 1939. An electrophoretic study of immune serums and purified antibody preparations. J. Exp. Med. 69: 119-13l. VAN WEEMAN, B. , and SCHUURS, A. H. W. N. 1971. Immunoassay using antigenenzyme conjugates.

Some of these humoral proteins are always present; others can be rapidly induced upon infection. Adaptive Immune System Unlike the nonadaptive system, the adaptive immune system provides resistance that is improved by repeated infections ofthe same pathogen. 1). Although both defenses respond specifically to most foreign substances, generally only one response is favored. The cellular immune response is primarily effective against parasites, intracellular viral infections, cancer cells, and foreign tissue, whereas the humoral response is favored in extracellular phases of bacterial and viral infections.

Lenhoff, pp. 155-190, Plenum Press, New York. ; CARBONARA, A. ; and HEREMANS, J. F. 1965. Immunochemical quantitation of antigens by single radial immunodiffusion. Immunochemistry 2:235-254. NAKANE, P. , and PIERCE, G. B. 1966. Enzyme-labeled antibodies preparation and application for the localization of antigens. J. Histochem. Cytochem. 14:929-931. NGo, T. , and LENHOFF, H. M. 1985. Enzyme-Mediated Immunoassay. Plenum Press, New York. References 23 ODELL, W. D. 1983. Principles of in vitro bioassays.

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