By Kaiyo Takubo
Esophageal ailments have lately turn into a spotlight of medical curiosity specifically because of a rise within the variety of instances of Barrett's esophagus. This publication offers a accomplished description of the esophagus according to many works released in English in addition to in jap. issues diversity from the embryology and constitution of the esophagus, to benign ailments and diverse esophageal infections, to esophageal carcinoma, together with Barrett's esophagus.
Not in simple terms the various appealing colour illustrations of pathological research via such potential as cytology, immunohistochemistry, and electron microscopy, but in addition the big variety of endoscopic photographs within the booklet make readers instantly conscious of its medical relevance. This ebook presents a useful resource of knowledge for pathologists, researchers, and training endoscopists.
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Extra resources for Pathology of the Esophagus: An Atlas and Textbook
Terminal portion of an esophageal gland proper. Clear mucous cells and dark serous cells form demilunes Table 2-1. Summary of the results of various staining procedures of components of the esophageal glands proper Alcian blue/ SC CEA LF S-100 Actin PAS/Mucicarmine Mucous cells Serous cells Oncocytes Myoepithelial cells Peripheral ductal epithelium in the submucosa Ductal stratiﬁed cuboidal epithelium in the lamina propria HID − − − − − − − − − + − − − + − + − − − + + − − − +/− − − − + − + − − − − − − − − − − − SC, secretory component; CEA, carcinoembryonic antigen; LF, lactoferrin; S-100, S-100 protein; PAS, periodic acid–Schiff; HID, high-iron diamine; +, positive; −, negative The glands are thought to secrete bicarbonate and epidermal growth factor (EGF) and, similar to the secretions of major and minor salivary glands, these have a role in supporting the mucosal squamous epithelium.
This author has also found that quite a number are actually mixed, containing both mucous and serous cells (Fig. 2-37). Also, a monograph, published about 50 years ago, reported that the esophageal glands proper are mixed glands that contain serous cells (Yokochi et al. 1954), but they are still described as mucous glands in most current textbooks. There are also oncocytes and myoepithelial cells in the terminal portions of these glands. Inﬁltrating plasma cells and lymphocytes can often be seen in the stroma and around excretory ducts in the terminal portions.
2-12. Cross sections of two axons are seen in the intercellular spaces of the prickle cells. One of them is surrounded by Schwann cells. b Schema of free ending nerves. The ﬁbers reaching the subepithelial plexus emanate from the submucosal plexus. The axons are surrounded by Schwann cell processes for a short distance through the basement membrane and then leave the Schwann cells among the epithelial cells. The axons are very circuitous a b Fig. 2-14. Esophagogastric junction of the clear-cut demarcation type.